CDK8-IN-13
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CDK8-IN-13

SKU T72029-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 1,006 CAD

Products Details

Product Description

– CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity. CDK8-IN-13 induces apoptosis and reduces the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 exhibits anti-tumour activity.

Web ID

– T72029

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H11N3O

References

– Zhang XX, et al. Discovery of a novel oral type Ⅰ CDK8 inhibitor against acute myeloid leukemia. Eur J Med Chem. 2023 ; 251:115214.

CAS Number

– 918523-75-8

Molecular Weight

– C14H11N3O

Compound Purity

– 0.9919

SMILES

– C(N)(=O)C=1C=C(C=2C=C3C(=NC2)NC=C3)C=CC1

Pathway

– Cell Cycle/Checkpoint|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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