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CDK8-IN-1
$350 – $2,250
Products Details
Product Description
– CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.
Web ID
– HY-103492
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C11H8F3N3O
References
– [1]Han X, et al. Discovery of potent and selective CDK8 inhibitors through FBDD approach. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4488-4492.
CAS Number
– 1629633-48-2
Molecular Weight
– 255.20
Compound Purity
– 99.77
SMILES
– NC(C1=C(C(F)(F)F)C(C2=CC=NC=C2)=CN1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– CDK
Isoform
– CDK8
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
