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Products Details
Product Description
– CDK2-IN-19 (Compound 32) is a selective and orally active CDK2 inhibitor (Ki: 0.18 nM). CDK2-IN-19 shows anticancer activity in mice bearing OVCAR3 tumors[1].
Web ID
– HY-155966
Shipping
– Room temperature
Molecular Formula
– C20H21FN6O4S
References
– [1]Mingshuo Zeng, et al. Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2). ACS Med. Chem. Lett. 2023.
Molecular Weight
– 460.48
SMILES
– FC(C=C(S(=O)(NC)=O)C=C1)=C1NC2=NC=C3C(N=C(C(N4C[C@@H](OC)[C@@H]4C)=O)C=C3)=N2.FC(C=C(S(=O)(NC)=O)C=C5)=C5NC6=NC=C7C(N=C(C(N8C[C@H](OC)[C@H]8C)=O)C=C7)=N6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
