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CCT245232

$180$1,200

Products Details

Product Description

– CCT245232 is a potent inhibitor of heat shock factor 1 (HSF1). HSF1 is the master regulator of the heat shock response, in which multiple genes are induced in response to temperature increase and other stresses. CCT245232 has the potential for the research of proliferative diseases, such as cancer (extracted from patent WO2015049535A1)[1].

Web ID

– HY-144867

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C27H23N3O4

References

– [1]Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. Patent WO2015049535A1.

CAS Number

– 1693731-14-4

Molecular Weight

– 453.49

Compound Purity

– 99.38

SMILES

– O=C(C1=CC=C2N=C(C)C=CC2=C1)NC3=CC(NC(C4=CC=C5OCCOC5=C4)=O)=CC=C3C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– HSP

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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