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CCR6 antagonist 1
$90 – $650
Products Details
Product Description
– CCR6 antagonist 1 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs)[1].
Web ID
– HY-151435
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H12F3NO2
References
– [1]Maria Grazia Martina, et al. Discovery of small-molecules targeting the CCL20/CCR6 axis as first-in-class inhibitors for inflammatory bowel diseases. Eur J Med Chem. 2022 Aug 29;243:114703.
CAS Number
– 588674-64-0
Molecular Weight
– 319.28
Compound Purity
– 99.55
SMILES
– O=C(C1=C(C)C2=CC=CC=C2O1)NC3=CC=C(C(F)(F)F)C=C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : ≥ 100 mg/mL
Target
– CCR
Isoform
– CCR6
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
