Cardiogenol C (hydrochloride)

$60$720

Products Details

Product Description

– Cardiogenol C hydrochloride is a potent cell-permeable pyrimidine inducer which prompts the differentiation of ESCs into cardiomyocytes (EC50=100 nM)[1]. Cardiogenol C hydrochloride also acts cardiomyogenic on already lineage-committed progenitor cell types with a limited degree of plasticity. Cardiogenol C hydrochloride is a useful cardiomyogenic agent and can be used as a tool to improve cardiac repair by cell transplantation therapy in animal models[2].

Web ID

– HY-12319A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C13H17ClN4O2

References

– [1]Wu X, et al. Small molecules that induce cardiomyogenesis in embryonic stem cells.J Am Chem Soc. 2004 Feb 18;126(6):1590-1.|[2]Mike AK, et al. Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Cell Physiol Biochem. 2014;33(1):205-21.

CAS Number

– 1049741-55-0

Molecular Weight

– 296.75

Compound Purity

– 99.76

SMILES

– [H]Cl.COC1=CC=C(NC2=NC=CC(NCCO)=N2)C=C1

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– DMSO : ≥ 59 mg/mL|H2O : 2 mg/mL (ultrasonic)

Target

– Wnt;β-catenin

Pathway

– Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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