Carbacyclin

$620

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Products Details

Product Description

– Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation.

Web ID

– HY-112322

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C21H34O4

References

– [1]Takasuka M, et al. FTIR spectral study of intramolecular hydrogen bonding in thromboxane A2 receptor agonist (U-46619), prostaglandin (PG)E2, PGD2, PGF2 alpha, prostacyclin receptor agonist (carbacyclin), and their related compounds in dilute CCl4 solution: structure-activity relationships. J Med Chem. 1994 Jan 7;37(1):47-56.|[2]Whittle BJ, et al. Carbacyclin–a potent stable prostacyclin analogue for the inhibition of platelet aggregation. Prostaglandins. 1980 Apr;19(4):605-27.|[3]Kuroda T, et al. Carbacyclin induces carnitine palmitoyltransferase-1 in cardiomyocytes via peroxisome proliferator-activated receptor (PPAR) delta independent of the IP receptor signaling pathway. J Mol Cell Cardiol. 2007 Jul;43(1):54-62.

CAS Number

– 69552-46-1

Molecular Weight

– 350.49

Compound Purity

– 99.0

SMILES

– O=C(O)CCC/C=C1C[C@@]2([H])C[C@@H](O)[C@H](/C=C/[C@@H](O)CCCCC)[C@@]2([H])C1

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease; Endocrinology

Solubility

– 10 mM in DMSO

Target

– Prostaglandin Receptor

Isoform

– IP

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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