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Capmatinib xHCl
Price range: 48 CAD through 538 CAD
Products Details
Product Description
– Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
Web ID
– T8416
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H18ClFN6O
References
– Liu X , Wang Q , Yang G , et al. A Novel Kinase Inhibitor, INCB28060, Blocks c-MET-Dependent Signaling, Neoplastic Activities, and Cross-Talk with EGFR and HER-3[J]. Clinical Cancer Research, 2011, 17(22):7127-7138.
CAS Number
– 1029714-89-3
Molecular Weight
– C23H18ClFN6O
Compound Purity
– 0.9924
SMILES
– Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1
Pathway
– Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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