Calicheamicin

SKU T14858-1 mg Category Brand:

Price range: 365 CAD through 2,000 CAD

Products Details

Product Description

– Calicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.

Web ID

– T14858

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C55H74IN3O21S4

References

– Damelin M, et al. Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions. Clin Cancer Res. 2015 Sep 15;21(18):4165-73

CAS Number

– 108212-75-5

Molecular Weight

– C55H74IN3O21S4

Compound Purity

– 0.9822

SMILES

– [H][C@@]1(C[C@H](OC)[C@H](CO1)NCC)O[C@@H]1[C@@H](O)[C@H](NO[C@H]2C[C@H](O)[C@H](SC(=O)c3c(C)c(I)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](OC)[C@H]4O)c(OC)c3OC)[C@@H](C)O2)[C@@H](C)O[C@@]1([H])O[C@H]1C#CC=C/C#C[C@]2(O)CC(=O)C(NC(=O)OC)=C1C2=CCSSSC

Target

– Others

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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