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Cabozantinib hydrochloride
Price range: 59 CAD through 1,530 CAD
Products Details
Product Description
– Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
Web ID
– T5164
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H25ClFN3O5
References
– Yakes FM, et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol Cancer Ther, 2011, 10(12), 2298-2308.
CAS Number
– 1817759-42-4
Molecular Weight
– C28H25ClFN3O5
Compound Purity
– 0.9997
SMILES
– Cl.COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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