CA-074 methyl ester
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CA-074 methyl ester

SKU T3420-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 86 CAD through 1,728 CAD

Products Details

Product Description

– CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.

Web ID

– T3420

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H31N3O6

Citations

– 1. Wang Y, Chen Y Y, Gao G B, et al.Polyphyllin D “Punctures” Hypertrophic Lysosomes to Reverse Drug Resistance of Hepatocellular Carcinoma by Targeting Acid Sphingomyelinase.Molecular Therapy.2023 2. Li M, Bei Z C, Yuan Y, et al.In-cell bioluminescence resonance energy transfer (BRET)-based assay uncovers ceritinib and CA-074 as SARS-CoV-2 papain-like protease inhibitors.Journal of Enzyme Inhibition and Medicinal Chemistry.2024, 39(1): 2387417.

References

– Dietmar Steverding, et al. The Open Enzyme Inhibition Journal. 2011, 4:11-16.

CAS Number

– 147859-80-1

Molecular Weight

– C19H31N3O6

Compound Purity

– 0.9949

SMILES

– CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](C(C)CC)C(=O)N1CCC[C@H]1C(=O)OC

Target

– Others

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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