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Products Details
Product Description
– C-021 dihydrochloride is a potent CCR4 antagonist that effectively inhibits functional chemotaxis in humans and mice, with IC50 values of 140 nM and 39 nM, respectively.
Web ID
– T10639
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H43Cl2N5O2
References
– Yokoyama K, et al. Potent and orally bioavailable CCR4 antagonists: Synthesis and structure-activity relationship study of 2-aminoquinazolines. Bioorg Med Chem. 2009 Jan 1;17(1):64-73.
CAS Number
– 1784252-84-1
Molecular Weight
– C27H43Cl2N5O2
Compound Purity
– 0.9851
SMILES
– Cl.Cl.COc1cc2nc(nc(NC3CCCCCC3)c2cc1OC)N1CCC(CC1)N1CCCCC1
Target
– Others
Pathway
– GPCR/G Protein|||Immunology/Inflammation|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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