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BV6
Price range: 70 CAD through 1,363 CAD
Products Details
Product Description
– BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.
Web ID
– T6428
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C70H96N10O8
Citations
– 1. Xu H, Tang Z, Zuo Y, et al. Molecular dynamics simulation revealed the intrinsic conformational change of cellular inhibitor of apoptosis protein-1. Journal of Biomolecular Structure and Dynamics. 2020, 38(4): 975-984
2. Li Y, Lee H H, Jiang V C, et al.Potentiation of apoptosis in drug-resistant mantle cell lymphoma cells by MCL-1 inhibitor involves downregulation of inhibitor of apoptosis proteins.Cell Death & Disease.2023, 14(11): 714.
3. Zheng M, Zhai Y, Yu Y, et al.TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response.Cell Metabolism.2024
References
– Li W, et al. J Thorac Oncol. 2011, 6(11), 1801-1809.
CAS Number
– 1001600-56-1
Molecular Weight
– C70H96N10O8
Compound Purity
– 0.98
SMILES
– CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)NCCCCCCNC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C1CCCCC1)C(c1ccccc1)c1ccccc1
Pathway
– Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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