Butein

SKU T6427-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 925 CAD

Products Details

Product Description

– Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator. It sensitizes HeLa cells to Cisplatin by targeting FoxO3a via the AKT and ERK/p38 MAPK pathways.

Web ID

– T6427

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H12O5

Citations

– 1. Zhao L, Zhang W, Luan F, et al.Butein suppresses PD-L1 expression via downregulating STAT1 in non-small cell lung cancer.Biomedicine & Pharmacotherapy.2023, 157: 114030.

References

– Yang EB, et al. Biochem Biophys Res Commun, 1998, 17, 245(2), 435-438.

CAS Number

– 487-52-5

Molecular Weight

– C15H12O5

Compound Purity

– 0.996

SMILES

– Oc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)c(O)c1

Pathway

– Autophagy|||JAK/STAT signaling|||Angiogenesis|||Metabolism|||Apoptosis|||Tyrosine Kinase/Adaptors

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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