Bucladesine sodium

SKU T1418-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 670 CAD

Products Details

Product Description

– Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-inflammatory activity.

Web ID

– T1418

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H23N5NaO8P

Citations

– 1. Cui L, Xu F, Xu C, et al.Circadian gene Rev-erbα influenced by sleep conduces to pregnancy by promoting endometrial decidualization via IL-6-PR-C/EBPβ axis.Journal of Biomedical Science.2022, 29(1): 1-14. 2. Zhang L, Wan M, Tohti R, et al.Requirement of Zebrafish Adcy3a and Adcy5 in Melanosome Dispersion and Melanocyte Stripe Formation.International Journal of Molecular Sciences.2022, 23(22): 14182. 3. Zhao W, Xu C, Peng L, et al.cAMP/PKA signaling promotes AKT deactivation by reducing CIP2A expression, thereby facilitating decidualization.Molecular and Cellular Endocrinology.2023: 111946. 4. Chen L, Zhao W, Li M, et al.SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor.Reproduction.2023, 1(aop). 5. Xu C, Zhao W, Huang X, et al. TORC2/3-mediated DUSP1 upregulation is essential for human decidualization. Reproduction. 2021, 1(aop). 6. Jiang N X, Zhao W J, Shen H R, et al.Hyperinsulinemia impairs decidualization via AKT-NR4A1 signaling: new insight into polycystic ovary syndrome (PCOS)-related infertility.Journal of Ovarian Research.2024, 17(1): 1-13.

References

– Jung Y. Comparative Analysis of Dibutyric cAMP and Butyric Acid on the Differentiation of Human Eosinophilic Leukemia EoL-1 Cells. Immune Netw. 2015 Dec;15(6):313-8.

CAS Number

– 16980-89-5

Molecular Weight

– C18H23N5NaO8P

Compound Purity

– 0.9976

SMILES

– [NaH].CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1OC(=O)CCC

Target

– Others

Pathway

– Metabolism|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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