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BTZO-1
$101 – $395
Products Details
Product Description
– BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro[1].
Web ID
– HY-110084
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H8N2OS
References
– [1]Kimura H, et al. BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression.Chem Biol. 2010 Dec 22;17(12):1282-94.
CAS Number
– 99420-15-2
Molecular Weight
– 240.28
Compound Purity
– 99.69
SMILES
– O=C1N=C(C2=NC=CC=C2)SC3=CC=CC=C13
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 8.33 mg/mL (ultrasonic)
Target
– Apoptosis;Macrophage migration inhibitory factor (MIF)
Pathway
– Apoptosis;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
