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Products Details
Product Description
– BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.
Web ID
– T1947
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H32N6
Citations
– 1. Zhang G M, Huang S S, Ye L X, et al. Reciprocal positive regulation between BRD4 and YAP in GNAQ-mutant uveal melanoma cells confers sensitivity to BET inhibitors. Pharmacological Research. 2022: 106464.
References
– Cancer Res. 2009 Aug 1;69(15):6208-15. doi: 10.1158/0008-5472.CAN-09-0301. Epub 2009 Jul 28.
CAS Number
– 1092443-52-1
Molecular Weight
– C22H32N6
SMILES
– CC(C)c1cnn2c(NCc3ccccc3)cc(NCCCCCCN)nc12
Target
– Others
Pathway
– Cell Cycle/Checkpoint|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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