Download Files:
Products Details
Product Description
– BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), interacts with a VHL ligand via a linker to form the PROTAC VZ185 (targeting BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively)[1].
Web ID
– T17696
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H26N4O3
References
– Zoppi V, et al. Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7. J Med Chem. 2019 Jan 24;62(2):699-726.
CAS Number
– 2305379-66-0
Molecular Weight
– C22H26N4O3
SMILES
– O=C1C=2C=NC=CC2C(=CN1C)C=3C=C(OC)C(=C(OC)C3)CN4CCNCC4
Target
– Others
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
