BOS-172722

$220$1,400

Products Details

Product Description

– BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively. BOS-172722 also has potential for the study of various forms of breast cancer[1].

Web ID

– HY-112162

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C24H30N8O

References

– [1]ARYL SULFONOHYDRAZIDES. WO 2014037750 A1.

CAS Number

– 1578245-44-9

Molecular Weight

– 446.55

Compound Purity

– 98.65

SMILES

– CC1=CC2=CN=C(NC3=CC=C(C4=NN=CN4C)C=C3OCC)N=C2C(NCC(C)(C)C)=N1

Clinical Information

– Phase 1

Research Area

– Cancer

Solubility

– 1M HCl : 65 mg/mL (ultrasonic;adjust pH to 2 with HCl)|DMSO : 5 mg/mL (ultrasonic)

Target

– Mps1

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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