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BODIPY FL thalidomide

SKU HY-152231-10 mg Category Tags , ,

$450$1,400

Products Details

Product Description

– BODIPY FL thalidomide is a high-affinity fluorescent probe for the human cereblon protein with a Kd value of 3.6 nM[1]</sup.

Web ID

– HY-152231

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C37H43BF2N6O7

References

– [1]Lin W, et al. Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay. Bioconjug Chem. 2020 Nov 18;31(11):2564-2575.

CAS Number

– 2740620-18-0

Molecular Weight

– 732.58

Compound Purity

– 99.20

SMILES

– O=C(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)NCCCCCCCCNC(CCC4=CC=C5C=C6C(C)=CC(C)=[N]6[B+3]([F-])([N-]54)[F-])=O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Ligands for E3 Ligase

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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