Products Details

Product Description

– Bisindolylmaleimide II is a general inhibitor of all PKC subtypes[1].

Web ID

– HY-108604

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C27H26N4O2

References

– [1]Gassel M, et al. The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. J Biol Chem. 2004 May 28;279(22):23679-90.

CAS Number

– 137592-45-1

Molecular Weight

– 438.52

SMILES

– O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CN(CCC5N(C)CCC5)C6=C4C=CC=C6)NC3=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– PKC

Pathway

– Epigenetics;TGF-beta/Smad

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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