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BI-3406
Price range: 107 CAD through 3,088 CAD
Products Details
Product Description
– BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
Web ID
– T12979
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H25F3N4O3
Citations
– 1. Moghadamchargari Z, Shirzadeh M, Liu C, et al. Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants. Proceedings of the National Academy of Sciences. 2021, 118(12)
References
– Marco H Hofmann, et al. Abstract PL06-01: Discovery of BI-3406: A potent and selective SOS1::KRAS inhibitor opens a new approach for treating KRAS-driven tumors. December 2019.
CAS Number
– 2230836-55-0
Molecular Weight
– C23H25F3N4O3
Compound Purity
– 0.992
SMILES
– COc1cc2nc(C)nc(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)c2cc1O[C@H]1CCOC1
Target
– Others
Pathway
– MAPK|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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