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Product Description
– Bedaquiline (R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
Web ID
– T2585
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C32H31BrN2O2
Citations
– 1. Briffotaux J, Xu Y, Huang W, et al. A Hydrazine–Hydrazone Adamantine Compound Shows Antimycobacterial Activity and Is a Probable Inhibitor of MmpL3. Molecules. 2022, 27(20): 7130.
2. Wang G, Dong W, Lu H, et al. Enniatin A1, A Natural Compound with Bactericidal Activity against Mycobacterium tuberculosis In Vitro. Molecules. 2020, 25(1): 38
3. Dong W, Wang G, Bai Y, et al.Repurposing an Antioxidant to Kill Mycobacterium tuberculosis by Targeting the 50S Subunit of the Ribosome.Biomolecules.2023, 13(12): 1793.
References
– Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Apr 20.
CAS Number
– 843663-66-1
Molecular Weight
– C32H31BrN2O2
Compound Purity
– 0.9976
SMILES
– COC1=NC2=C(C=C(C=C2)Br)C=C1[C@@H](C3=CC=CC=C3)[C@](O)(C4=CC=CC5=C4C=CC=C5)CCN(C)C
Pathway
– Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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