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BAY-707
$310
Only 1000 item(s) left in stock.
Products Details
Product Description
– BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy[1].
Web ID
– HY-112081
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H20N4O2
References
– [1]Ellermann M, et al. Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.ACS Chem Biol. 2017 Aug 18;12(8):1986-1992.
CAS Number
– 2109805-96-9
Molecular Weight
– 288.34
SMILES
– O=C(NCC)C(N1)=CC2=C1N=CC=C2N3CCOC[C@@H]3C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
