BACE1-IN-4
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BACE1-IN-4

SKU T10452-25 mg Category Brand:

Price range: 5,232 CAD through 8,480 CAD

Products Details

Product Description

– BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), exhibiting greater selectivity for BACE1 over BACE2.

Web ID

– T10452

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H23F2N5O4S2

References

– Fujimoto K, et al. Structure-Based Design of Selective β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2. J Med Chem. 2019 May 23;62(10):5080-5095.

CAS Number

– 2361157-92-6

Molecular Weight

– C21H23F2N5O4S2

SMILES

– C[C@]1(C2(CCS(=O)(=O)CC2)CSC(N)=N1)C3=CC(NC(=O)C=4C=NC(OCF)=CN4)=CC=C3F

Target

– Others

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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