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Products Details
Product Description
– AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.
Web ID
– T22264
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H22N6O2
References
– Howard R T , Hemsley P , Petteruti P , et al. Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors[J]. ACS Chemical Biology, 2020, XXXX(XXX).
CAS Number
– 1825345-33-2
Molecular Weight
– C26H22N6O2
Compound Purity
– 0.9929
SMILES
– O=C(N1CCN(CC1)c1ncccc1C#N)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
Target
– ADC Linker
Pathway
– Chromatin/Epigenetic|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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