AZ31
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AZ31

SKU T19671-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 414 CAD

Products Details

Product Description

– AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.

Web ID

– T19671

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H28N4O3

References

– Kiesel BF, et al. LC-MS/MS assay for the simultaneous quantitation of the ATM inhibitor AZ31 and the ATR inhibitor AZD6738 in mouse plasma. J Pharm Biomed Anal. 2017 ; 138:158-165.

CAS Number

– 2088113-98-6

Molecular Weight

– C24H28N4O3

Compound Purity

– 0.9801

SMILES

– N([C@@H](C)C1CCOCC1)C=2C3=C(N=CC2C(N)=O)C=CC(=C3)C=4C=CC(COC)=NC4

Target

– Others

Pathway

– PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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