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AX20017
$40 – $432
Products Details
Product Description
– AX20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
Web ID
– HY-14987
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H16N2O2S
References
– [1]Walburger A, et al. Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. Science. 2004 Jun 18;304(5678):1800-4.|[2]Santhi N, et al. Insights from the molecular docking of withanolide derivatives to the target protein PknG from Mycobacterium tuberculosis. Bioinformation. 2011;7(1):1-4.|[3]Scherr N, et al. Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12151-6.
CAS Number
– 329221-38-7
Molecular Weight
– 264.34
Compound Purity
– 99.88
SMILES
– O=C(N)C1=C(NC(C2CC2)=O)SC3=C1CCCC3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 130 mg/mL (ultrasonic)
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
