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Auristatin E
Price range: 77 CAD through 358 CAD
Products Details
Product Description
– Auristatin E, a cytotoxic tubulin modifier, disrupts cell division by inhibiting tubulin polymerisation. This compound demonstrates potent and selective antitumor activities, serving as an MMAE analog and cytotoxin in antibody-drug conjugates.
Web ID
– T14348
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C40H69N5O7
References
– Francisco JA, et al. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood. 2003 Aug 15;102(4):1458-65.
CAS Number
– 160800-57-7
Molecular Weight
– C40H69N5O7
Compound Purity
– 0.9881
SMILES
– [H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1
Target
– CXCR
Pathway
– Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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