Download Files:
Products Details
Product Description
– Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. Ara-SH is used as the trigger to fabricate a smart Cytarabine and Venetoclax-coloaded nanoparticle (AV-NP) through self-assembly. Ara-SH exhibits remarkable synergistic antileukemia effects in vitro and in vivo[1].
Web ID
– HY-154971
Shipping
– Room temperature
Molecular Formula
– C12H17N3O6S
References
– [1]Lejiao Jia, et al. Smart and Generalizable Cytarabine Derivative-Triggered Nanoparticles for Synergistic Therapy of Relapsed/Refractory Acute Myeloid Leukemia. ACS Appl Mater Interfaces. 2023 Jun 14;15(23):27624-27637.
Molecular Weight
– 331.34
SMILES
– O=C(NC1=NC(N([C@@H]2O[C@@H]([C@H]([C@@H]2O)O)CO)C=C1)=O)CCS
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
