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APX-115 free base
Price range: 67 CAD through 1,904 CAD
Products Details
Product Description
– APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury.
Web ID
– T10353
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H17N3O
References
– Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8(43):74217-74232.
CAS Number
– 1270084-92-8
Molecular Weight
– C17H17N3O
Compound Purity
– 0.9839
SMILES
– CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1
Target
– Others
Pathway
– Metabolism|||Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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