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Products Details
Product Description
– APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
Web ID
– T70004
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H21N3O3
CAS Number
– 2002381-25-9
Molecular Weight
– C23H21N3O3
SMILES
– COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3C)c2cc1OC
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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