Download Files:
AP-1/NF-κB activation inhibitor 1
Price range: 107 CAD through 2,496 CAD
Products Details
Product Description
– AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation (IC50 = 1 μM), without blocking basal transcription driven by the β-actin promoter. It has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells [1].
Web ID
– T9656
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H11F3N4O4
References
– Palanki MS, et al. Novel inhibitors of AP-1 and NF-kappaB mediated gene expression: structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)++ +pyrimidi ne-5-carboxylate. Bioorg Med Chem Lett. 2000;1
CAS Number
– 188936-12-1
Molecular Weight
– C13H11F3N4O4
Compound Purity
– 0.9974
SMILES
– CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)C(F)(F)F
Pathway
– NF-κB|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
