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Products Details
Product Description
– Antiviral agent 36 (compound 27) is a potent dengue (DENV) and Zika (ZIKV) viruses inhibitor. Antiviral agent 36 inhibits replication of Zika and dengue virus with EC50s of 100 nM, 90 nM, 210 nM, and 120 nM for ZIKV-FLR, ZIKV-HN16, DENV-2, and DENV-3, respectively[1].
Web ID
– HY-155129
Shipping
– Room temperature
Molecular Formula
– C30H32N4O3
References
– [1]Md Ashraf-Uz-Zaman, et al. Quinazolinone Compounds Have Potent Antiviral Activity against Zika and Dengue Virus. J Med Chem. 2023 Aug 10;66(15):10746-10760.
Molecular Weight
– 496.60
SMILES
– O=C1N(C(/C=C/C2=NC(OC)=CC=C2)=NC3=CC=C(C=C31)N4CCOCC4)C5=CC=CC(C(C)(C)C)=C5
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
