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Products Details
Product Description
– Antitubulin agents-1 is an antitubulin agent that induces disruption of the microtubules (Microtubule/Tubulin) and increases α-tubulin acetylation. Antitubulin agents-1 has anticancer effects[1]. Antitubulin agent 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-151953
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H19N3O3
References
– [1]Arash Foroutan, et al. Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114895.
Molecular Weight
– 361.39
SMILES
– C#CCOC1=CC(N/C(C)=C2C(NN(C2=O)CC3=CC=CC=C3)=O)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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