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Product Description
– Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL[1].
Web ID
– HY-147919
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H14ClN5O3
References
– [1]Morcoss MM, et al. Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents. Bioorg Chem. 2020 Aug;101:103956.
CAS Number
– 2445277-57-4
Molecular Weight
– 419.82
SMILES
– O=C(C1=CC=C2C(N=C(C3=CC=C([N+]([O-])=O)C=C3)N2)=C1)N/N=C/C4=CC=C(Cl)C=C4
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Fungal
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
