Products Details

Product Description

– Antibacterial agent 93 (compound 36l) is a potent aminoacyl-tRNA synthetases (aaRS) inhibitor. Antibacterial agent 93 shows antibacterial activities against some gram-positive and -negative bacteria[1].

Web ID

– HY-146266

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C29H28Cl3N5O4

References

– [1]Cai Z, et al. Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. J Med Chem. 2022 Apr 14;65(7):5800-5820.

Molecular Weight

– 616.92

SMILES

– O=C(NC[C@@H](C1=CC(C2=CC=C(C=C2)Cl)=CC=C1)NC([C@@H](N)[C@@H](C)O)=O)CCN3C=NC4=C(C3=O)C=C(Cl)C(Cl)=C4

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Aminoacyl-tRNA Synthetase;Bacterial

Pathway

– Anti-infection;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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