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Products Details
Product Description
– Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM.
Web ID
– HY-14187
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H29I2NO3
Citations
– Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|Biotechnol Bioeng. 2021 Sep 3.|Cell. 2022 Dec 8;185(25):4801-4810.e13.|Cell. 2023 Nov 22;186(24):5363-5374.e16.|Ecotoxicol Environ Saf. 2021 Apr 1;212:111991.|Patent. US20180263995A1.|Front Bioeng Biotechnol. 2022 Mar 17;10:826093.|Viruses. 2021 Jun 28;13(7):1255.
References
– [1]Singh, B.N. and E.M. Vaughan Williams, The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol, 1970. 39(4): p. 657-67.|[2]Rosenbaum, M.B., et al., Clinical efficacy of amiodarone as an antiarrhythmic agent. Am J Cardiol, 1976. 38(7): p. 934-44.
CAS Number
– 1951-25-3
Molecular Weight
– 645.31
SMILES
– CCCCC1=C(C(C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)=O)C3=C(O1)C=CC=C3
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Cancer
Solubility
– 10 mM in DMSO
Target
– Autophagy;Potassium Channel
Pathway
– Autophagy;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
