Products Details

Product Description

– Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM.

Web ID

– HY-14187

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C25H29I2NO3

Citations

– Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|Biotechnol Bioeng. 2021 Sep 3.|Cell. 2022 Dec 8;185(25):4801-4810.e13.|Cell. 2023 Nov 22;186(24):5363-5374.e16.|Ecotoxicol Environ Saf. 2021 Apr 1;212:111991.|Patent. US20180263995A1.|Front Bioeng Biotechnol. 2022 Mar 17;10:826093.|Viruses. 2021 Jun 28;13(7):1255.

References

– [1]Singh, B.N. and E.M. Vaughan Williams, The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol, 1970. 39(4): p. 657-67.|[2]Rosenbaum, M.B., et al., Clinical efficacy of amiodarone as an antiarrhythmic agent. Am J Cardiol, 1976. 38(7): p. 934-44.

CAS Number

– 1951-25-3

Molecular Weight

– 645.31

SMILES

– CCCCC1=C(C(C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)=O)C3=C(O1)C=CC=C3

Clinical Information

– Launched

Research Area

– Cardiovascular Disease; Cancer

Solubility

– 10 mM in DMSO

Target

– Autophagy;Potassium Channel

Pathway

– Autophagy;Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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