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AMG PERK 44
Price range: 104 CAD through 1,728 CAD
Products Details
Product Description
– AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy. It also inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), making it useful for cancer research.
Web ID
– T10299
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C34H29ClN4O2
References
– Smith AL, et al. Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK). J Med Chem. 2015 Feb 12;58(3):1426-41.
CAS Number
– 1883548-84-2
Molecular Weight
– C34H29ClN4O2
Compound Purity
– 0.9981
SMILES
– Cl.Cc1ccc2cc(ccc2n1)-c1c(C)ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c1N
Target
– Others
Pathway
– Autophagy|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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