AMD 3465
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AMD 3465

SKU T14208-25 mg Category Brand:

Price range: 2,432 CAD through 4,000 CAD

Products Details

Product Description

– AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells.

Web ID

– T14208

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H38N6

References

– Hatse S, et al. AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor. Biochem Pharmacol. 2005 Sep 1;70(5):752-61.

CAS Number

– 185991-24-6

Molecular Weight

– C24H38N6

SMILES

– N=1C=CC=CC1CNCC2=CC=C(C=C2)CN3CCNCCCNCCNCCC3

Target

– Others

Pathway

– Microbiology/Virology|||Proteases/Proteasome

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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