Products Details

Product Description

– AJH-836 is an activator of Munc13-1 and PKC ε/α (Kd: 4.5 nM for PKCα) . AJH-836 triggers the translocation of Munc13-1 from the cytoplasm to the plasma membrane. AJH-836 can be used for research of neurodegenerative diseases[1].

Web ID

– HY-149490

Shipping

– Room temperature

Molecular Formula

– C22H38O5

References

– [1]Das J, Yet al. Activation of Munc13-1 by Diacylglycerol (DAG)-Lactones. Biochemistry. 2023 Aug 31.

CAS Number

– 388621-67-8

Molecular Weight

– 382.53

SMILES

– CC(C)(C)C(OCC(C/C1=CCC(CC(C)C)CC(C)C)(CO)OC1=O)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– PKC

Pathway

– Epigenetics;TGF-beta/Smad

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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