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AhR agonist 2
$100 – $950
Products Details
Product Description
– AhR agonist 2 (Compound 12a) is a potent agonist of aryl hydrocarbon receptor (AhR) with an EC50 of 0.03 nM. AhR agonist 2 induces rapid nuclear enrichment of AhR, triggers the transcription of downstream genes and promote skin barrier repair. AhR agonist 2 has the potential for the research of psoriasis[1].
Web ID
– HY-144339
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C12H7Br2N3
References
– [1]Tian C, et al. Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model. Eur J Med Chem. 2022;231:114122.
Molecular Weight
– 353.01
Compound Purity
– 99.53
SMILES
– BrC1=CC=C(C=C1)C2=NN3C=C(C=CC3=N2)Br
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 70°C)
Target
– Aryl Hydrocarbon Receptor
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
