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Products Details
Product Description
– AG6033 is a potential novel CRBN modulator. AG6033 suppresses various tumor cells by modulating the interactions between CRBN and various antitumor target proteins. AG6033 can cause GSPT1 and IKZF1 degradation. AG6033 induces CRBN-dependent cytotoxic effect[1].
Web ID
– HY-143435
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H23N5O4
References
– [1]Xiong F, Kong L, Chen L, et al. Discovery of potential novel CRBN modulators by virtual screening and bioassay. Eur J Med Chem. 2022 Apr 5;236:114355.
CAS Number
– 329706-62-9
Molecular Weight
– 517.53
SMILES
– O=C(N/N=C1C(N(CC(NC2=CC=CC=C2)=O)C3=C1C=CC=C3)=O)C4=CC=CC(NC(C5=CC=CC=C5)=O)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
