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Products Details
Product Description
– AC-42 is a poent M1 muscarinic selective allosteric agonist with EC50s of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively[1].
Web ID
– HY-118806
Shipping
– Room temperature
Molecular Formula
– C20H31NO
References
– [1]Marlene A Jacobson, et al. The M1 muscarinic receptor allosteric agonists AC-42 and 1-[1′-(2-methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one bind to a unique site distinct from the acetylcholine orthosteric site. Mol Pharmacol. 2010 Oct;78(4):648-57.
CAS Number
– 244291-63-2
Molecular Weight
– 301.47
SMILES
– O=C(CCCN1CCC(CC1)CCCC)C2=CC=CC=C2C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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