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A947
Price range: 1,712 CAD through 5,656 CAD
Products Details
Product Description
– A947 is a potent and selective SMARCA2 protein hydrolysis-targeted chimeric molecule (PROTAC) that induces the degradation of SMARCA2 by binding to VHL E3 ubiquitin ligase, with significant antitumor activity in vivo and in vitro, especially in SMARCA4-mutant non-small cell lung cancer (NSCLC) cells.
Web ID
– T74686
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C61H76N12O7S
CAS Number
– 2378056-80-3
Molecular Weight
– C61H76N12O7S
Compound Purity
– 0.9884
SMILES
– O(C1=CC(N2C3CN(CC2CC3)C=4C=C(N=NC4N)C5=C(O)C=CC=C5)=CC=N1)[C@H]6C[C@H](OC7CCN(CC8CCN(CC8)C=9C=C([C@H](C(=O)N%10[C@H](C(N[C@@H](C)C%11=CC=C(C=C%11)C=%12SC=NC%12C)=O)C[C@@H](O)C%10)C(C)C)ON9)CC7)C6
Pathway
– PROTAC|||Chromatin/Epigenetic
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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