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Products Details
Product Description
– A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 μM), an effect that is reduced in the presence of vitamin B6(EC50= <100 μM).
Web ID
– T36833
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C6H8N2O2
References
– Ohtoyo, M., Tamura, M., Machinaga, N., et al.Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levelsLipids51(10)1207-1216(2016)
CAS Number
– 1331754-16-5
Molecular Weight
– C6H8N2O2
SMILES
– CC(=O)c1ncc(CO)[nH]1
Pathway
– Others
Product type
– Small Compound
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