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Products Details
Product Description
– A3AR modulator 1 (MRS8054) is an orally active A3 adenosine receptor (A3AR) (Adenosine Receptor) positive allosteric modulator (PAM). A3AR modulator 1 greatly enhances Cl-IB-MECA-stimulated [35S]GTPγS binding Emax[1].
Web ID
– HY-151899
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H25IN4
References
– [1]Lucas B Fallot, e al. Structure-Activity Studies of 1 H-Imidazo[4,5- c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators. J Med Chem. 2022 Nov 24;65(22):15238-15262.
Molecular Weight
– 484.38
SMILES
– CCCC(C1=NC2=C(C3=C(N=C2NC4=CC=C(C=C4)I)C=CC=C3)N1)CCC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor
Isoform
– Adenosine A3 receptor (A3R)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
