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Products Details
Product Description
– A031, a potent PROTAC androgen receptor (AR) degrader, demonstrates significant efficacy with an IC50 value under 0.25 μM for AR protein degradation. Additionally, it exhibits an inhibitory impact on tumor growth in zebrafish models of human prostate cancer (VCaP) [1].
Web ID
– T74745
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C50H61ClN10O7S
CAS Number
– 2682255-44-1
Molecular Weight
– C50H61ClN10O7S
SMILES
– [H][C@]12CC[C@]([H])(C[C@@H](C1)Oc1ccc(C#N)c(Cl)c1)N2C(=O)c1cnc(nc1)N1CCN(CCOCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@@H](C)c2ccc(cc2)-c2scnc2C)C(C)(C)C)CC1
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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