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Aβ-IN-1
Price range: 336 CAD through 1,525 CAD
Products Details
Product Description
– Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharmacokinetic profile.
Web ID
– T63208
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C35H49N
References
– Albuquerque HMT, et al. Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Med Chem Lett. 2022;13(3):443-448.
CAS Number
– 2766509-32-2
Molecular Weight
– C35H49N
Compound Purity
– 0.9914
SMILES
– C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C=5C(CC2)=NC=6C(C5C)=CC=CC6)[H])[H]
Pathway
– Neuroscience|||Stem Cells|||Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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